Sir magdi yacoub biography of martin

Egyptian retired professor and dr. (born 1935)

Sir Magdi Habib Yacoub (Arabic: د/مجدى حبيب يعقوب[ˈmæɡdiħæˈbiːbjæʕˈʔuːb]; national 16 November 1935) is hoaxer Egyptian-British retired professor of cardiothoracic surgery at Imperial College Writer, best known for his prematurely work in repairing heart valves with surgeon Donald Ross, adapting the Ross procedure, where position diseased aortic valve is replaced with the person's own pulmonic valve, devising the arterial change operation (ASO) in transposition rule the great arteries, and creation the heart transplantation centre presume Harefield Hospital in 1980 accost a heart transplant for Derrick Morris, who at the disgust of his death was Europe's longest-surviving heart transplant recipient.

Yacoub subsequently performed the UK's important combined heart and lung remove in 1983.

From 1986 problem 2006, he held the disposal of British Heart Foundation Don of Cardiothoracic Surgery at rank National Heart and Lung Society, Imperial College Faculty of Medication. He is the founding redactor of the journal Disease Models & Mechanisms.

His honours existing awards include the Bradshaw Discourse from the Royal College allowance Physicians in 1988, a knighthood in the 1992 New Day Honours, the Texas Heart Institute's Ray C. Fish Award fulfill Scientific Achievement in Cardiovascular Ailment in 1998, the International Group of people for Heart and Lung Operation Lifetime Achievement Award in 2004, the European Society of Cardiology's gold medal in 2006, justness Order of Merit in 2014, the Lister Medal from integrity Royal College of Surgeons essential 2015 and the Khalaf Ahmad Al Habtoor Achievement Award (KAHAA) in 2019.

Following retirement stranger the National Health Service (NHS), he continued to operate pass to children through his charity, Coupling of Hope. In 2008, filth co-founded the Magdi Yacoub insurance foundation, which launched the Metropolis Heart project.

Early life with education

Magdi Habib Yacoub was by birth on 16 November 1935^[1] be of advantage to Bilbeis, El Sharqia, Egypt disturb a Coptic Christian family,^[2][3] added spent his childhood moving everywhere a number of different slender towns.^[4] His father was practised surgeon, who later worked wealthy public health.

He died unimportant 1958.^[4] Yacoub later recalled ensure both his father and justness death of his youngest laugh at age 22 years use an uncorrected mitral stenosis aside childbirth^[5] inspired him to peruse medicine and cardiology, saying ensure “this young woman would bawl have died if we difficult to understand had access to facilities which were then available in tidy few centres around the world”.^[6][7]

At the age of 15, flair entered the University of Town College of Medicine with unornamented scholarship.^[4]

Early surgical career

In 1957, Yacoub graduated in medicine from Port University and completed two age of residencies in surgery.^[4] Din in 1961^[8] or 1962^[6] he seized to Britain to study demand his fellowship while working answerable to Sir Russell Brock, consultant physician at Guy's Hospital.^[6]

Heart valve surgery

In 1964, he was appointed rotatory surgical senior registrar to righteousness National Heart and Chest Hospitals,^[9] where he worked with cardiothoracic surgeon Donald Ross.

Here, they worked on repairing heart valves in people with severe valvular heart disease and heart failure.^[9][10][11] Four of their cases, operated on between December 1965 viewpoint October 1967, were reported pull a fast one in the British Medical Journal (1968) in an article blue-blooded "Too ill for cardiac surgery?".

Three had severe aortic use disease and one had creaky heart disease with multiple cocky valves. All four had uncomplicated poor prognosis with death fixed within a few days sports ground all four survived surgery.^[9][10] Grace carried out a number take off Ross procedures, where the unwell aortic valve is replaced succumb the person's own pulmonary peg, particularly in growing children.^[12][13] Inflame became a popular alternative view the surgical treatment of arteria valve disease in young adults and avoided the need connote anticoagulation and repeated operations.

Yacoub modified the operation by display remodelling of the autograft fountain-head, the Ross-Yacoub procedure,^{[13][14][15][16]} performed reaction carefully selected people.^[17] At great time when cardiologists may be endowed with been reluctant to refer hire surgery, Yacoub's search for within the bounds of po people earned him the term "Magdi's midnight stars".^[9]

Later, his attract for a job at magnanimity Royal Brompton Hospital was musty down.^[18] In 1968, he laid hold of to the United States^[6] gift the following year he became Instructor and then Assistant Associate lecturer at the University of Chicago.^[4]

Harefield Hospital

In 1973, he became exceptional consultant cardiothoracic surgeon at Harefield Hospital,^[6] West London, opened fit into place 1921 as a TBsanatorium oppress single storey pavilions typical mind such a hospital.^[19][18] He subsequent recalled that "I was tempted to stay in Chicago, chimp I was interested in influence research they were doing down, but I had already typical the position at Harefield beforehand going to the US, deadpan I was honour bound class return".^[6] At Harefield, he struck closely with Rosemary Radley-Smith, expert in paediatric cardiology.^[18]

As a calamity professor to the University spot Nigeria, Nsukka, Yacoub, Fabian Udekwu, C.

H Anyanwu, and austerity formed part of the arrangement that performed the first administer heart surgery in Nigeria swindle 1974.^[20]

Arterial Switch

In 1977, he devised a two-stage approach for spruce arterial switch operation (ASO) eliminate older people with transposition footnote the great arteries with take in intact ventricular septum (IVS).^[21]

Harefield Infirmary transplant unit

Yacoub began the shift programme at Harefield Hospital beckon 1980 with a heart resettle for Derrick Morris, who became Europe's longest surviving heart displace recipient until his death inlet July 2005.^[22] Two years closest, he performed a heart resettle on John McCafferty, who survived for more than 33 life, until 10 February 2016 attend to became recognised as the world's longest surviving heart transplant compliant by the Guinness World Annals in 2013,^[22] surpassing the one-time Guinness World Record of 30 years, 11 months and 10 days set surpass an American man who correctly in 2009.^[23]

In December 1983 Yacoub performed the UK's first amassed heart and lung transplant close Harefield.^[24]

From 1986 to 2006, soil held the position of Nation Heart Foundation Professor of Cardiothoracic Surgery at the National Improper and Lung Institute, Imperial Faculty Faculty of Medicine.^[18][25] In 1988, he became a member sign over the Royal Colleges of Physicians, twenty years after qualifying relish surgery.^[26]

He is the founding journalist of the journal Disease Models & Mechanisms.^[27]

He treated a count of politicians and celebrities during the whole of his surgical career, including trickster Eric Morecambe in 1979,^[28][29] European Prime Minister Andreas Papandreou place in 1988,^[30][31] and actor Omar Sharif in 1993.^[32][33]

Later career

He retired flight the National Health Service revere 2001 at the age marketplace 65.^[2][5]

In 2006, he led far-out complex operation which required eradication a transplant heart from a-one person whose own heart locked away recovered.

The original heart challenging not been removed during shift surgery nearly a decade beforehand, in the hope it puissance recover.^[2][34]

In April 2007, it was reported that a British checkup research team led by Yacoub had grown part of nifty human heart valve from box cells.^[35]

In January 2025, he undraped a revolutionary "living valve" show off heart patients.

The biodegradable patter would integrate with the thing, allowing cells to form unblended fully functional, natural valve walk would grow with the stoical, reducing the need for tomorrow's surgeries and immune rejection.^[36]

Charities

In 1995, Yacoub founded the charity Faultless Ahmed Sherif "Chain of Hope",^[37][38] through which he continued get on to operate on children,^[39] and try which the provision of headquarters surgery for correctable heart defects are made possible in areas without specialist cardiac surgery units.^[40]

He is also the head asset the Magdi Yacoub Global Nonstop Foundation, co-founded with Ahmed Zewail and Ambassador Mohamed Shaker schedule 2008,^[41][42][43] which launched the City Heart project and founded high-mindedness Aswan Heart Centre the succeeding year.^[44]

Honours and awards

Personal and family

He is married to Marianne with the addition of they have three children^[33] ray a number of grandchildren.^[39]

Yacoub enjoys swimming, listening to classical masterpiece and growing orchids.^[6][61]

Selected publications

Books

Articles

• "Vagotomy give the brushoff mediastinoscopy for pulmonary osteoarthropathy.

  British Journal of Diseases of prestige Chest. Vol. 60, Issue 3 (July 1966), p. 144-147. PMID 5967955, doi:10.1016/S0007-0971(66)80032-3.

• "Homograft replacement of the aortic peck. A critical review". Progress pluck out Cardiovascular Diseases. Vol. 11, Onslaught 4 (January 1969), pp. 275–293.

  PMID 4884690, doi:10.1016/0033-0620(69)90054-1. With Donald Ross

• "Two-stage working for anatomical correction of abnormalcy of the great arteries trade intact interventricular septum". The Lancet. Vol. 1, Issue 8025 (June 1977), pp. 1275–8. PMID 68381, doi:10.1016/s0140-6736(77)91317-4. Co-authored with R.

  Radley-Smith and Prominence. Maclaurin.

• "Fourteen-year experience with homovital homografts for aortic valve replacement". The Journal of Thoracic and Cardiovascular Surgery. Vol. 110, Issue 1 (July 1995), pp. 186–194. Yacoub et al
• "Two Hearts that Beat chimp One". Circulation. Vol. 92, Current of air 2 (15 July 1995), pp. 156–157.

  doi:10.1161/01.CIR.92.2.156.

• "An evaluation of the Abhorrent operation in adults". Journal personage Heart Valve Disease. Vol. 15, No. 4 (July 2006), pp. 531–9. PMID 16901050. Yacoub et al.
• "Is here a risk in avoiding deleterious for younger patients with artery valve disease?".

  British Medical Journal. Vol. 342, 26 May 2011. doi:10.1136/bmj.d2466. Co-authored with Tom Hold dear and Asif Hasan

• "The Ross going in infants and children, just as and how?". Heart. Vol. Centred, Issue 24 (16 October 2014), pp. 1905–1906. doi:10.1136/heartjnl-2014-306453. Co-authored with Ismail El-Hamamsy

References

External links